In August 2019 researchers from the UK and Australia published their review of the medical and scientific literature to assess the safety and effectiveness of e-cigarettes as a means of stopping smoking. Currently
there are over 7000 flavours of e-cigarette refills, many of which may cause an adverse effect on human cells and tissues. A total of 58 studies were included in the review. Results showed that flavourings and nicotine content of e-cigarettes have both been linked to chronic lung disease and cardiovascular disease. Although e-cigarettes are advertised as an effective way to give up smoking there is no agreement on this, although the first study looking at this specifically did report some success. However, there is also evidence that using e-cigarettes leads to a 3-fold increase in the risk of smoking traditional cigarettes in the future.
Worku D, Worku E. A narrative review evaluating the safety and efficacy of e-cigarettes as a newly marketed smoking cessation tool. SAGE Open Med. 2019 Aug 18;7:2050312119871405.