Low vitamin D levels may increase the risk of fertility problems in individuals with polycystic ovary syndrome

In May 2019 researchers from Turkey published the results of their study to assess whether vitamin D levels may play a role in the fertility problems in women with polycystic ovary syndrome. A total of 274 infertile and 111 fertile women with polycystic ovary syndrome were included in the study. The infertile and fertile groups of individuals were matched by age, BMI and an assessment of their insulin resistance. Vitamin D levels were assessed in all individuals. Results showed that vitamin D levels were significantly lower and vitamin D deficiency more common in the infertile group compared to the fertile group. A further analysis revealed that when insulin resistance or obesity was present, vitamin D levels were reduced further. Thus, in polycystic ovary syndrome, lower vitamin D levels may play a role in fertility problems in this group of individuals.

Kokanalı D et al. Serum Vitamin D Levels in Fertile and Infertile Women with Polycystic Ovary Syndrome. Geburtshilfe Frauenheilkd. 2019 May;79(5):510-516

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