Vitamin D levels of under 30 ng/ml appear to be associated with higher levels of LP-PLA2, a new marker for vascular-specific inflammation, in individuals with diabetes type 2

In June 2019 researchers from China published the results of their study to assess the association between vitamin D levels and Lp-PLA2, a new marker for vascular-specific inflammation, in individuals with diabetes type 2. A total of 196 individuals were included in the study, and their height, weight, BMI, blood pressure and vitamin D and Lp-PLA2 levels were assessed. Results showed that those individuals who had insufficient levels of vitamin D (under 30 ng/ml) had higher LP-PLA2 levels than those whose vitamin D levels fell within the normal range. In fact, the lower the vitamin D level, the higher the level of Lp-PLA2. However, no significant association between Lp-PLA2 and vitamin D levels was noted in individuals whose vitamin D levels fell within the normal range.

Zhang Q et al. Role of vitamin D in risk factors of patients with type 2 diabetes mellitus. Med Clin (Barc). 2019 Jun 26. pii: S0025-7753(19)30347-1.

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