In July 2018 researchers from Canada published their review of the medical scientific literature to assess the effect of vitamin D supplementation on cardiovascular disease risk factors. A total of 81 studies were included in the review. Results showed that vitamin D supplementation significantly reduced blood pressure levels, parathyroid hormone, C-reactive protein, total cholesterol, LDL(bad)-cholesterol and triglycerides as well as significantly increasing HDL(good)-cholesterol. These findings suggest that vitamin D supplementation may protect against cardiovascular disease through improving risk factors, including high blood pressure, elevated parathyroid hormone, dyslipidaemia, and inflammation.
Mirhosseini N et al. Vitamin D Supplementation, Serum 25(OH)D Concentrations and Cardiovascular Disease Risk Factors: A Systematic Review and Meta-Analysis. Front Cardiovasc Med. 2018 Jul 12;5:87.