Long-term exposure to polycyclic aromatic hydrocarbons may result in thyroid function impairment

In January 2018 researchers from Iran published the results of their study to assess the association of urinary levels of polycyclic aromatic hydrocarbons with thyroid function in children and adolescents. A total of 150 children and adolescents, aged 6-18 years, were involved in the study. Blood samples were assessed for thyroid function and urine samples for polycyclic aromatic hydrocarbons, including 1-hydroxynaphthalene, 2-hydroxynaphthalene, 9-hydroxyphenanthrene, and 1-hydroxypyrene. Results showed that higher levels of polycyclic aromatic hydrocarbons were significantly associated with a higher level of thyroid stimulating hormone. The researchers therefore concluded that long-term exposure to polycyclic aromatic hydrocarbons may result in thyroid function impairment.

Kelishadi R et al. Is there any association between urinary metabolites of polycyclic aromatic hydrocarbons and thyroid hormone levels in children and adolescents? Environ Sci Pollut Res Int. 2018 Jan;25(2):1962-1968

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