Old folk tales “Grape or grain but never the twain” and “Beer before wine and you’ll feel fine; wine before beer and you’ll feel queer” are not true

In February 2019 researchers from Germany and the UK published the results of their study to investigate the influence of the combination and order of beer and wine consumption on hangover intensity. Ninety individuals (aged 19-40 years; 50% female) were divided into three groups. Group 1, comprising 31 individuals, consumed beer up to a breath alcohol concentration ≥0.05% and then wine to a breath alcohol concentration of ≥0.11%, whereas Group 2, also comprising 31 individuals, consumed wine first and then the beer. Group 3, comprising 28 individuals, acted as a control group and consumed either only beer or only wine. Approximately one-week later Groups 1 and 2 were switched to the opposite drinking order and those in Group 3 who had drunk only beer on the first occasion switched to wine and vice versa. Results showed that neither the type nor the order of consumed alcoholic beverages significantly affected hangover intensity whereas perceived drunkenness and vomiting were the strongest predictors for hangover intensity.

Köchling J1 et al. “Grape or grain but never the twain? A randomized controlled multiarm matched-triplet crossover trial of beer and wine. Am J Clin Nutr. 2019 Feb 1;109(2):345-352

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