Vitamin B12 that is applied to the oral cavity via toothpaste enters the circulation and improves the vitamin B12 status markers in the blood of vegans who are at higher risk of vitamin B12 deficiency

In March 2017 researchers from Germany and Denmark published the results of their study to assess the effect of a vitamin B12-fortified toothpaste on B12 vitamin levels in vegans. A total of 66 vegans completed the study, with 36 individuals using a vitamin B12 toothpaste and 30 a control toothpaste. Blood levels of vitamin B12 and various vitamin B12 status markers, were assessed at the start and end of a 12-week period. Results showed that not only were the levels of vitamin B12 higher in those using the vitamin B12 toothpaste, but the changes that had occurred over the 12-week period were also greater than those seen in the control group. In addition, the vitamin B12 markers significantly improved over the 12-week period, with the changes being greater in the vitamin B12 toothpaste group than the control group. A further analysis revealed that the changes in vitamin B12 markers were more prominent in vegans who reported that they had not taken vitamin B12 supplements.

Siebert AK et al. Vitamin B-12-fortified toothpaste improves vitamin status in vegans: a 12-wk randomized placebo-controlled study. Am J Clin Nutr. 2017 Mar;105(3):618-625

Leave a Reply