In April 2019 researchers from Iran published their review of the medical scientific literature to assess the effect of garlic supplementation on inflammatory biomarkers in adults. A total of 16 studies were included in the review. The garlic dose ranged from 12 to 3600 mg/d, and the length of time the supplementation was taken ranged between 2-52 weeks, Results showed that garlic supplementation appeared to significantly reduce levels of C-reactive protein, Tumor Necrosis Factor, and Interleukin-6 but had no significant effect on adiponectin and leptin.
Darooghegi Mofrad M et al. Garlic Supplementation Reduces Circulating C-reactive Protein, Tumor Necrosis Factor, and Interleukin-6 in Adults: A Systematic Review and Meta-analysis of Randomized Controlled Trials. J Nutr. 2019 Apr 1;149(4):605-618